Researchers at Columbia University College of Dental Medicine have engineered exosomes to carry CRISPR, significantly enhancing the delivery of genome editing components to specific cells and tissues.
Including BRCA1 testing with prenatal carrier screening could identify people at risk of breast, ovarian, and pancreatic cancer at a time when cancer screening could save their lives.
Columbia genome engineers are designing a CRISPR-based gene therapy with potential to prevent blindness in anyone with retinitis pigmentosa, a condition caused by more than 80 different genes.
Many Black Americans thought to have a high risk of developing kidney disease possess a genetic variant that eradicates the extra risk, a new study from Columbia researchers has found.
CUMC researchers have found direct evidence of a link between prenatal vitamin A deficiency and postnatal airway hyperresponsiveness, a hallmark of asthma.
High-risk pregnant women being recruited for a clinical trial that aims to give parents detailed information about genetic abnormalities found in utero.
Two Columbia faculty are part of a 61-member international research team that discovered 25 epilepsy-causing mutations in new and previously identified genes.