A new study finds that many of our genes, if disabled by a mutation, have a surprising ability to turn on backup genes to compensate for lost functions.
A “loopy” discovery in bacteria is raising fundamental questions about the makeup of our own genome. And revealing a potential wellspring of material for new genetic therapies.
Researchers at Columbia University College of Dental Medicine have engineered exosomes to carry CRISPR, significantly enhancing the delivery of genome editing components to specific cells and tissues.
Including BRCA1 testing with prenatal carrier screening could identify people at risk of breast, ovarian, and pancreatic cancer at a time when cancer screening could save their lives.
Richard S. Mann, PhD, and colleagues have solved the longstanding puzzle of why a single transcription factor can turn on many genes in a test tube, but only a few genes in a live organism.
Columbia University Medical Center (CUMC) researchers have found the first direct evidence that an acquired trait can be inherited without any DNA involvement.