A new study finds that many of our genes, if disabled by a mutation, have a surprising ability to turn on backup genes to compensate for lost functions.
A “loopy” discovery in bacteria is raising fundamental questions about the makeup of our own genome. And revealing a potential wellspring of material for new genetic therapies.
Researchers at Columbia University College of Dental Medicine have engineered exosomes to carry CRISPR, significantly enhancing the delivery of genome editing components to specific cells and tissues.
Including BRCA1 testing with prenatal carrier screening could identify people at risk of breast, ovarian, and pancreatic cancer at a time when cancer screening could save their lives.
College of Physicians & Surgeons Dean Lee Goldman discusses his new book, which examines the role DNA plays in attempting to treat diabetes, obesity, and cardiovascular disease.
P&S researcher Wendy Chung and colleagues find genetic mutations that explain why many children with congenital heart disease also have neurodevelopmental disorders.
Funding from the ALS Association and the Tow Foundation will be used by the New York Genome Center to determine the entire genetic sequence of people with ALS who donated their tissues after death.
A significant proportion of children with chronic kidney disease (CKD) have unsuspected chromosomal imbalances, including DNA anomalies that have been linked to neurocognitive disorders.
Using advanced DNA sequencing methods, researchers have identified a new gene that is associated with sporadic amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease.
Two Columbia University Medical Center faculty members were present today when President Obama provided details of the precision medicine initiative he announced during this year’s State of the Union address.
Biogen Idec and Columbia University Medical Center have formed a $30 million strategic alliance to conduct genetics discovery research on the underlying causes of disease and to identify new treatment approaches.