Established two decades ago, the essential tremor brain bank at Columbia has been instrumental in revealing the source and biology of a common but understudied neurodegenerative disorder.
Analysis of 1.6 million brain cells from older adults has captured the cellular changes that occur in Alzheimer’s early stages, revealing potential new targets and routes for prevention.
An international study shows as many as one-quarter of unresponsive patients with brain injuries have some level of awareness, a finding that could spur development of new treatments.
Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy, a finding that could lead to a new therapy for a disease that affects 1 in 6,000 children.
Columbia’s researchers have opened a trial of a noninvasive, focused ultrasound approach to open the blood-brain barrier, enabling higher concentrations of an effective drug to enter the brain.
Immune cells in the brain must rearrange a part of their cytoskeleton before they can perform their jobs, a finding that may lead to new ways to slow some brain diseases.
Indira Turney, an associate research scientist in the Department of Neurology, is studying how lived experiences affect they way the brain ages in diverse populations.
Even in people with complete paralysis after spinal cord injury, some nerves fibers are preserved. A Columbia physician-scientist is developing a new way to salvage those fibers and restore movement.