Ten years ago, a Columbia postdoc identified a simple nutrient that can alleviate Parkinson’s disease symptoms in mice by rewiring the brain. It’s finally being put to the test in people.
Timely discussions about the goals of care ensure that nursing home residents receive care that aligns with their wishes but are less likely in homes with a higher percentage of Black residents.
Analysis of 1.6 million brain cells from older adults has captured the cellular changes that occur in Alzheimer’s early stages, revealing potential new targets and routes for prevention.
A new study finds that mitochondria in our brain cells frequently fling their DNA into the cells' nucleus, where the mitochondrial DNA integrates into chromosomes, possibly causing harm.
Columbia biomedical engineers are collaborating with orthopedic surgeons to build a living replacement knee to be tested in clinical trials within five years.
Columbia genome engineers are designing a CRISPR-based gene therapy with potential to prevent blindness in anyone with retinitis pigmentosa, a condition caused by more than 80 different genes.
The CUIMC Healthy Aging Initiative will host its first Healthspan Extension Summit later this spring, highlighting the work of CUIMC researchers in basic, clinical, and population health sciences.
Columbia researchers discovered stem cells in mice that are essential in maintaining healthy cartilage inside joints, but the cells go missing with age or after injury.
A new study in mice shows that new neurons created in the brain during adulthood are needed to maintain working memory—the temporary “sticky notes” of the brain.
A study led by Columbia researchers finds that deficiency of taurine, a molecule produced in our bodies, drives aging, and taurine supplements can improve health and increase lifespan in animals.